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CAS : 52490-15-0 Amiodarone Intermediate Assay 98.0% MIN GMP standard
Chemical Name : 2 - Butyl - 3 - ( 4 - Hydroxybenzoyl ) benzofuran
CAS No. 52490-15-0
Synonyms : 2 - Butyl - 3 - benzofuranyl p - hydroxyphenyl ketone ; ( 2 - Butyl - 3 - benzofuranyl ) ( 4 - hydroxyphenyl ) - methanone
Molecular Formula : C19H18O3
Molecular Weight : 294.34
Appearance: Off white to white powder
Melting Point: 116 Deg C MIN
Loss on drying: Not More than 0.5%
Total Impurities: Not More than 2.0%
Assay: Not Less than 98.0%
Usuage: Amiodarone Intermediate
Description: Amiodarone is used to treat acute and also chronic arrhythmias, both in supraventricular and ventricular arrhythmias. A Belgium company called Labaz developed amiodarone in 1961. Amiodarone was commonly used in Europe to treat arrhythmias, but remained unapporoved by FDA in USA till December 1985. Amiodarone is one of the few drugs approved by FDA without rigorous randomized clinical trials.
2 - Butyl - 3 - ( 4 - Hydroxybenzoyl ) benzofuran CAS No. 52490-15-0 is one of its intermediates. There are several synthesis routes to manufacture this intermediate but some routes are protected by the patents in some countries including Europe, USA and China. We strictly obey the laws and our commercial products are manufactured without infringing such patents. But anyway, the buyers should know the patent status by themselves. We promise to supply the real route of synthesis to the buyers. The buyers should take the risks of patent infringement by themselves.
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