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1129634 44 1,
1441670 89 8
CAS : 1129634-44-1 Ledipasvir Intermediates Optical Purity NLT 99.0% Powder
Chemical Name : ( S ) - 5 - ( TERT - BUTOXYCARBONYL ) - 5 - AZASPIRO [ 2 , 4 ] HEPTANE - 6 - CARBOXYLIC ACID
CAS No. 1129634-44-1
Synonyms : ( S ) - 5 - BOC - 5 - AZASPIRO [ 2 , 4 ] HEPTANE - 6 - CARBOXYLIC ACID ; ( S ) - 5 - BOC - 5 -AZASPIRO [ 2 . 4 ] HEPTANE - 6 - CARBOXYLIC ACID ; ( 6S ) - 5 - [ ( tert - butoxy ) carbonyl ] - 5 - azaspiro [ 2 . 4 ] heptane - 6 - carboxylic acid ; ( 6S ) - 5 - ( TERT - BUTOXYCARBONYL ) - 5 - AZASPIRO [ 2 . 4 ] HEPTANE - 6 - CARBOXYLIC ACID
Molecular Formula : C12H19NO4
Molecular Weight : 241.29
Appearance: White to off-white powder
Any individual impurities: NMT 0.5%
Total impurities: NMT 2.0%
Chemical purity: NLT 98.0%
Optical purity: NLT 99.0%
Usuage: Ledipasvir Intermediate
Description: Ledipasvir is one of the active pharmaceutical ingredients (API) of branded drug Harvoni (the other one is Sofosbuvir). It was approved in June 2014 in USA. It is marketed by Gilead Sciences Inc. Harvoni is used to hepatitis C virus of genotypes 1a or 1b without PEG-interferon or ribavirin. Ledipasvir is an inhibitor of HCV NS5A protein. The Q4 Harvoni sales in 2015 was US Dollars 3.35 billion.
( S ) - 5 - ( TERT - BUTOXYCARBONYL ) - 5 - AZASPIRO [ 2 , 4 ] HEPTANE - 6 - CARBOXYLIC ACID CAS No. 1129634-44-1is one of its intermediates. Ledipasvir is protected by some patents in some countries and areas such as USA, Europe and China. We strictly obey the laws and our product is only for R&D purpose. The buyers should determine the patent status and take the risks of patent infringement by themselves.
Competitive Advantage: Produced under cGMP conditions, support customers’ registrations.