Edaravone CAS 9 25 8 5 - Methyl - 2 - Phenyl - 4H - Pyrazol - 3 - One

Edaravone CAS : 89-25-8 5 - Methyl - 2 - phenyl - 4H - pyrazol - 3 - one

Name : Edaravone

Synonym : MCI-186

CAS No . : 89-25-8

Chemical Name : 5 - Methyl - 2 - phenyl - 4H - pyrazol - 3 - one ; 3 - metyl - 1 - phenyl - 2 - pyrazolin - 5 - one

Molecular Formula : C10H10N2O

Molecular Weight : 174.2

Description :

Edaravone is the active pharmaceutical ingredient of the brand drug names Radicava and Radicut. It belongs to the drug class miscellaneous central nervous system agent and  is used to treat Amyotrophic Lateral Sclerosis ( ALS ). It is an antioxidant. Oxidative stress is might to be part of the process kills neurons in people with amyotrophic lateral sclerosis. It is also used to help recovery form stroke in Japan. 

In late 1980s free radical scavenger edaravone was first developed to treat stroke to prevent the swelling of the brain. Mitsubishi Pharma marketed it in 2001 in Japan. Mitsubishi Tanabe started phase III clnical trial for amyotrophic lateral sclerosis ( ALS ) in 2011. Japan approved this use in 2015. FDA and EU granted the company the Orphan Drug Designation for edaravone in 2016. US FDA approved it to treat ALS in May 2017.

The drug might be protected by patents in some courtires or areas. We only sell it to non patent protected countries or areas. The sale to patent protection countries and areas is only for R & D purpose. The buyers should take all responsiblity of patent status in his countries or areas.