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Sacubitril , LCZ 696 CAS : 149709-62-6 GMP DMF
Name : Sacubitril
CAS No . : 149709-62-6
Synonyms : AHU - 377 , LCZ696
Chemical Name : 4 - [ [ ( 2S , 4R ) - 5 - ethoxy - 4 - methyl - 5 - oxo - 1 - ( 4 - phenylphenyl ) pentan - 2 - yl ] amino ] - 4 - oxobutanoic acid
Molecular Formula : C24H29NO5
Molecular Weight : 411.5
Sacubitril combined with valsartan ( Sacubitril / Valsartan ) are the active pharmaceutical ingredients of Novartis' brand drug Entresto. It is used for hear failure. Sacubitril is a neprilysin inhibitor and valsartan is an angiotensin receptor blocker. These two are 1 : 1 combined by molecular count.
US FDA approved the drug Entresto in July 7, 2015. It is also approved in Europe Union.
The drug might be protected by patents in some courtires or areas. We only sell it to non patent protected countries or areas. The sale to patent protection countries and areas is only for R & D purpose. The buyers should take all responsiblity of patent status in his countries or areas.
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