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ZD - 6 Rosuvastatin Intermediates CAS No 147118-39-6 off white powder

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ZD - 6 Rosuvastatin Intermediates CAS No 147118-39-6 off white powder

China ZD - 6 Rosuvastatin Intermediates CAS No 147118-39-6  off white powder supplier

Large Image :  ZD - 6 Rosuvastatin Intermediates CAS No 147118-39-6 off white powder

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Place of Origin: China
Certification: cGMP standard

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Minimum Order Quantity: 500Grams
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Detailed Product Description
Usage: Rosuvastatin Calcium Intermediate CAS: 147118-39-6
Short Code: ZD - 6 Name: Methyl ( + ) - ( 3R ) - 7 - [ 4 - ( 4 - Fluorophenyl ) - 6 - Isopropyl - 2 - ( N - Methyl - N - Methanesulfonylamino ) Pyrimidin - 5 - Yl ] - 3 - Hydroxy - 5 - Oxo - 6 ( E ) - Heptenoate
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rosuvastatin lactone

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rosuvastatin sodium

ROSUVASTATIN INTERMEDIATE : 

 

Methyl (+)-(3-R)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesul fonylamino)pyrimidin-5-yl)-3-hydroxy-5-oxo-6(E)-heptenoate

 

CAS No . : 147118-39-6

 

Synonyms : ZD - 6 ; 5 - Oxo rosuvastatin Methyl ester ; ( R,E ) - Methyl 7 - ( 4 - ( 4 - fluorophenyl ) - 6 - isopropyl-2- ( N - Methylmethylsulfonamino ) pyrimidin - 5 - yl ) - 3 - hydroxy - 5 - oxohept - 6 - enoate ; Methyl 7 -[ 4 - ( 4 - FLUOROPHENYL ) - 6 - ISO - PROPYL -2 - ( N - METHYL - N - METHYLSULFONYLAMINO ) PYRIMIDIN - 5 - YL ] - ( 3R,5R ) - DIHYDROXY - ( E ) - 6 - HEPTENATE ; Methyl 7 - [ 4 - ( 4 - fluorophenyl ) - 6 - isopropyl - 2 - ( N - Methyl - N - Methylsulfonylamino) pyrimidin - 5 - yl ]- ( 3R ) - 3 - hydroxy - 5 - oxo - ( E ) - 6 - heptenate

 

Molecular Formula : C23H28FN3O6S

 

Molecur Weight : 493.55

 

Description: Rosuvastatin Calcium is the active ingredient (API) of branded drug Crestor. It was innovated by the Japanese drug maker Shionogi and cooperated the marketing with AstraZeneca. Rosuvastatin Calcium is the new generation of statins drugs after Lovastatin, Simvastatin and Atorvastatin. It is a fully synthesized product and used to treat high cholesterol and to prevent cardiovascular disease. Some persons also call it super statin to express its good effect. The annual sales of Crestor exceed US dollars 6.6 Billion in 2014. The first generic version of Crestor will launch in US in 2016.

 

Methyl (+)-(3-R)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesul fonylamino)pyrimidin-5-yl)-3-hydroxy-5-oxo-6(E)-heptenoate  CAS No . : 147118-39-6 is one of its intermediates. There are several synthesis routes to manufacture this intermediate but some routes are protected by the patents in some countries including Europe, USA and China. We strictly obey the laws and our commercial products are manufactured without infringing such patents. But anyway, the buyers should know the patent status by themselves. We promise to supply the real route of synthesis to the buyers. The buyers should take the risks of patent infringement by themselves.

 

Competitive Advantage: Produced under cGMP conditions, support customers’ registrations, Approved by many esteemed companies

 

 

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