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145783 14 8,
1156491 10 9
CAS : 145783-15-9 Ticagrelor Intermediates Purity 98.0% min Powder
Chemical Name : 4 , 6 - Dichloro - 2 - (propylthio ) pyrimidine - 5 - amine
Synonyms : 4 , 6 - Dichloro - 2 - ( propylthio ) pyrimidinamine
CAS No. : 145783-15-9
Molecular Formula : C7H9Cl2N3S
Molecular Weight : 238.14
Appearance: Almost White to pale brown yellow powder
Loss on drying: NMT 0.5%
Sulfated ash: NMT 0.2%
Total impurities: NMT 2.0%
Purity: NLT 98.0%
Usuage: Ticagrelor Intermediate
Description: Ticagrelor is the active pharmaceutical ingredients (API) of branded drug Brillinta, Briliquie and Possia. It was approved in December 3 2010 in Euorpe and in July 2011in USA by FDA . It is marketed by AstraZeneca. Ticagrelor is a platelet aggregation inhibitor and used to prevent thrombotic events such as stroke or heart attack in people with acutate coronary syndrome or myocardial infarction with ST elevation. Ticagrelor is better than clopidogrel for P2Y12 inhibition treatment in patients with NSTE-ACS treated with early invasive strategy and/or coronary stenting according to AHA/ACC Guidelines (09/2014).
4,6-DICHLORO-2-(PROPYLTHIO)PYRIMIDINE-5-AMINE CAS No. 145783-15-9 is one of Ticagrelor intermediates. Ticagrelor is protected by some patents in some countries and areas such as USA, Europe and China. We strictly obey the laws and our product is only for R&D purpose. The buyers should determine the patent status and take the risks of patent infringement by themselves.
Competitive Advantage: Produced under cGMP conditions, support customers’ registrations.