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C39H46F2N2O5Si2 CAS 272778 12 8 Ezetimibe Intermediates E3 cGMP Standard

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C39H46F2N2O5Si2 CAS 272778 12 8 Ezetimibe Intermediates E3 cGMP Standard

China C39H46F2N2O5Si2 CAS 272778 12 8 Ezetimibe Intermediates E3 cGMP Standard supplier

Large Image :  C39H46F2N2O5Si2 CAS 272778 12 8 Ezetimibe Intermediates E3 cGMP Standard

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Place of Origin: China
Certification: GMP condition

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Detailed Product Description
CAS: 272778-12-8 Usage: Ezetimibe Intermediate
Molecular Formula: C39H46F2N2O5Si2 Short Code: E3
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CAS : 272778-12-8 Ezetimibe Intermediates cGMP standard C39H46F2N2O5Si2

 

Chemical Name : 3 - [ ( 2R , 5S ) - 5 - ( 4 - fluorophenyl ) - 2 - { ( S ) - [ ( 4 - fluorophenyl ) amino ] } [ 4 - ( trimethylsilyl ) - oxy ] pentyl ] methyl - 1 - 2 - oxo - 5 - ( trimethylsilyl ) - oxo ] pentyl ] - 4 - phenyl - ( 4S ) - 2 - oxazolidinone

 

CAS No . : 272778-12-8

 

Synonyms: 3 - [ ( 2R , 5S ) - 5 - ( 4 - Fluorophenyl ) - 2 - [ ( S ) - [ ( 4 - fluorophenyl ( amino) ] ] [ 4 - [ trimethylsilyl ] - oxy ] phenyl ] methyl ] - 1 - oxo - 5 - [ ( trimethylsily ) - oxy ] pentyl ] - 4 - phenyl - ( 4S ) - 2 - oxazolidinone

 

Short Code : E3

 

Molecular Formula : C39H46F2N2O5Si2

 

Molecular Weight : 716.96

 

Usage : Ezetimibe Intermediates

 

Description: Ezetimibe is the active pharmaceutical ingredient (API) of branded drug Zetia, or one of the active pharmaceutical ingredients (API) of branded drug Liptruzet (the other API is atorvastatin) or Vytorin (the other API is simivastatin). It was innovated by Schering-Plough Pharmaceuticals and co-marketed with Merck/MSD. Ezetimibe is used to reduce the amount of cholesterol and other fatty substances in the blood. It may be used alone or with other statins such as atorvastatin and simivastatin.

 

3 - [ ( 2R , 5S ) - 5 - ( 4 - fluorophenyl ) - 2 - { ( S ) - [ ( 4 - fluorophenyl ) amino ] } [ 4 - ( trimethylsilyl ) - oxy ] pentyl ] methyl - 1 - 2 - oxo - 5 - ( trimethylsilyl ) - oxo ] pentyl ] - 4 - phenyl - ( 4S ) - 2 - oxazolidinone CAS No . : 272778-12-8 is one of its intermediates. There are several synthesis routes to manufacture this intermediate but some routes are protected by the patents in some countries. We strictly obey the laws and our commercial products are manufactured without infringing such patents. But anyway, the buyers should know the patent status by themselves. We promise to supply the real route of synthesis to the buyers. The buyers should take the risks of patent infringement by themselves.

 

Competitive Advantage: Produced under cGMP conditions, support customers’ registrations.

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