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98.0 % min Velpatasivir Intermediates powder CAS 1378391-45-7

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98.0 % min Velpatasivir Intermediates powder CAS 1378391-45-7

China 98.0 % min Velpatasivir Intermediates powder  CAS 1378391-45-7 supplier

Large Image :  98.0 % min Velpatasivir Intermediates powder CAS 1378391-45-7

Product Details:

Place of Origin: China
Certification: cGMP standard

Payment & Shipping Terms:

Minimum Order Quantity: 500Grams
Packaging Details: Drum
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Detailed Product Description
Usage: Velpatasvir Intermediates CAS: 1378391-45-7
GMP: Yes
High Light:

1378388 16 9

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1438383 89 1

CAS No . : 1378391-45-7 Velpatasivr Intermediate NLT 98.0 % 

 

Chemical Name : ( 2S , 4S ) - tert - Butyl 2 - ( 5 - ( 2S , 5S ) - 1 - ( ( S ) - 2 - (methoxycarbonyl ) amino ) - 3 - methylbutanoyl ) - 5 - methylpyrrolidin - 2 - yl ) - 1 , 11 - dihydroisochromeno [ 4 ' , 3 ' : 6 , 7 ] naphtho [ 1 , 2 - d ] imidazol - 9 - yl ) - 4 - ( methoxymethyl ) pyrrolidine - 1 - carboxylate

 

Synonyms : TERT - BUTYL ( 2S , 4S ) - 2 - ( 5 - ( 2 - ( ( 2S , 5S ) - 1 - ( ( METHOXYCARBONYL ) - L -VALYL ) - 5 - METHYLPYRROLIDIN - 2 - YL ) - 1 , 11 - DIHYDROISOCHROMENO [4 ' , 3 ' : 6 , 7 ] NAPHTHO - [ 1 , 2 - D ] IMIDAZOL - 9 - YL ) - 1H - IMIDAZOL - 2 - YL ) - 4 - ( METHOXYMETHYL ) PYRROLIDINE - 1 - CARBOXYLATE

 

CAS No. 1378391-45-7

 

Molecular Formula : C44H53N7O7

 

Molecular Weight : 791.93

 

Usage: Velpatasvir intermediate

 

Specifications:

 

Appearance: Almost White to pale brown yellow powder

Loss on drying: NMT 0.5%

Sulfated ash: NMT 0.2%

Total impurities: NMT 2.0%

Purity: NLT 98.0%

 

Description:

 

Velpatasvir is one of the active pharmaceutical ingredients (API) of branded drug Epclusa (the other one is Sofosbuvir). It was approved in June 2016 in USA and July 2016 in Europe. It is marketed by Gilead Sciences Inc. Epclusa is used to treat adults with chronic hepatitis C virus. Chronic hepatitis C virus has 6 different genotypes. Epclusa is the first drug to treat all these 6 genotypes. The sales of its first 2 days reaches the record of USD64 million.

 

TERT - BUTYL ( 2S , 4S ) - 2 - ( 5 - ( 2 - ( ( 2S , 5S ) - 1 - ( ( METHOXYCARBONYL ) - L -VALYL ) - 5 - METHYLPYRROLIDIN - 2 - YL ) - 1 , 11 - DIHYDROISOCHROMENO [4 ' , 3 ' : 6 , 7 ] NAPHTHO - [ 1 , 2 - D ] IMIDAZOL - 9 - YL ) - 1H - IMIDAZOL - 2 - YL ) - 4 - ( METHOXYMETHYL ) PYRROLIDINE - 1 - CARBOXYLATE CAS No. 1378391-45-7 is one of its intermediates. Velpatasvir is protected by some patents in some countries and areas such as USA, Europe and China. We strictly obey the laws and our product is only for R&D purpose. The buyers should determine the patent status and take the risks of patent infringement by themselves.

 

Competitive Advantage: Produced under cGMP conditions, support customers’ registrations.

 

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